Serotonin Receptor 5-HT3A Affects Development of Bladder Innervation and Urinary Bladder Function
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چکیده
منابع مشابه
Serotonin Receptor 5-HT3A Affects Development of Bladder Innervation and Urinary Bladder Function
The autonomic and sensory nervous systems are required for proper function of all visceral organs, including the lower urinary tract (LUT). Despite the wide prevalence of bladder dysfunction, effective treatment options remain limited. Pelvic innervation regenerative strategies are promising, but surprisingly little is known about the molecular factors driving the development of bladder innerva...
متن کاملDynamic Expression of Serotonin Receptor 5-HT3A in Developing Sensory Innervation of the Lower Urinary Tract
Sensory afferent signaling is required for normal function of the lower urinary tract (LUT). Despite the wide prevalence of bladder dysfunction and pelvic pain syndromes, few effective treatment options are available. Serotonin receptor 5-HT3A is a known mediator of visceral afferent signaling and has been implicated in bladder function. However, basic expression patterns for this gene and othe...
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One of the rarest tumors involving the urinary bladder is the pheochromocytoma. A case of pheochromocytoma of the urinary bladder in a young female suffering from headache and cystitis for many years is reported. Twenty-four hour urine VMA was normal. The patient was never hypertensive except during surgical manipulation of the tumor. Biopsy of the bladder resulted in massive hemorrhage.
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Complex organization of CNS and PNS pathways is necessary for the coordinated and reciprocal functions of the urinary bladder, urethra and urethral sphincters. Injury, inflammation, psychogenic stress or diseases that affect these nerve pathways and target organs can produce lower urinary tract (LUT) dysfunction. Numerous neuropeptide/receptor systems are expressed in the neural pathways of the...
متن کاملPHEOCHROMOCYTOMA OF URINARY BLADDER: REPORT OF A CASE AND BRIEF REVIEW OF THE LITERATURE
A case of pheochromocytoma of the bladder is presented with a r eview of the literature. We discuss general management principles of bladder pheochromocytoma. Successful diagnosis and treatment of this lesion requires a high index of suspicion based upon the patient's symptom complex, allowing preoperative preparation prior to surgical treatment.
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2017
ISSN: 1662-453X
DOI: 10.3389/fnins.2017.00690